Drostanolone Propionate, commonly known by the brand name Masteron, is an anabolic-androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It is known for its strong androgenic properties and mild anabolic effects, making it popular in both medical and bodybuilding contexts.
Chemical Background
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Chemical Name: 2α-methyl-17β-hydroxy-5α-androstan-3-one propionate
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Type: Injectable anabolic steroid
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Derivative: Dihydrotestosterone (DHT)
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Ester: Propionate (short-acting, rapid release)
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Anabolic Rating: ~62–130
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Androgenic Rating: ~25–40
Medical Uses
Originally, Drostanolone Propionate was developed for breast cancer treatment in women, as it has anti-estrogenic properties.
It has also been used in the past to help preserve muscle mass in patients with wasting diseases, although today it is less common in mainstream medicine due to newer alternatives.
Performance & Physique Enhancement
In the athletic and bodybuilding world, Drostanolone Propionate is valued for:
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Muscle Hardening: Enhances muscle density and definition, especially when body fat is low.
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Dry Look: Does not cause water retention, making it ideal for pre-contest preparation.
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Strength Maintenance: Helps retain strength during calorie deficits.
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Mild Anti-Estrogen Effect: May reduce estrogenic side effects from other steroids.
Key Benefits
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Promotes lean muscle mass without excessive weight gain.
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Improves vascularity and muscle hardness.
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Minimal risk of estrogen-related side effects (since it’s a DHT derivative).
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Short ester allows fast results and easier control over dosing.
Common Dosage in Bodybuilding (for reference only – not medical advice)
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Men: 300–500 mg per week, typically split into injections every other day.
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Women: 50–100 mg per week, in carefully monitored cycles to avoid virilization.
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Cycle Length: 6–8 weeks is common due to its potency and androgenic effects.
Potential Side Effects
Despite its mild anabolic nature, Drostanolone Propionate is still a potent hormone and can cause side effects, including:
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Androgenic: Acne, oily skin, hair loss (in genetically predisposed individuals).
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Virilization in women: Deepened voice, body hair growth, menstrual changes.
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Natural Testosterone Suppression: Requires post-cycle therapy (PCT).
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Cholesterol Impact: Can reduce HDL (“good” cholesterol) and increase LDL.
Detection & Legality
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Detection Time: Approximately 3 weeks.
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WADA Status: Banned in professional sports.
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Legal Status: Controlled substance in many countries; possession/use may be illegal without a prescription.




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